BIOPHYSIQUE DE L AUDITION EBOOK!
Biophysique (4° Éd.) de la PACES à l'ECN. Authors: AURENGO André, PETITCLERC Thierry, KAS Aurélie. Language: Français. Cover of the book Biophysique. Physique et biophysique (PCEM). 3, Biophysique sensorielle: audition, vision, équilibre vestibulaire, Volume 3. Front Cover. M. Burgeat. Masson, - Abstract: A detrimental perceptive consequence of damaged auditory sensory hair cells consists in a pronounced masking effect exerted by low-frequency.
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Hair bundles of vestibular sensory cells analyzed using scanning electron microscopy. The expression of the therapeutic gene was detected 48 hours after injection. The team demonstrated that a single injection to restore the production and localization of the missing protein in biophysique de l audition cells successfully improved hearing and balance functions in the young mice.
These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex the proteins cadherin 23, protocadherin 15, myosin VIIA and harmoninas required for the mechanoelectrical transduction apparatus of the hair biophysique de l audition to function correctly.
This suggests that the time window for effectively treating USH1 syndrome using gene therapy may be larger than initially thought.
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